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Inflammation-induced alterations in maternal-fetal Heme Oxygenase (HO) are associated with sustained innate immune cell dysregulation in mouse offspring

Heme oxygenase-1 (HO-1) is an evolutionarily conserved stress response enzyme and important in pregnancy maintenance, fetal and neonatal outcomes, and a variety of pathologic conditions. Here, we investigated the effects of an exposure to systemic inflammation late in gestation [embryonic day (E)15....

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Publicado en:PLoS One
Autores principales: Ozen, Maide, Zhao, Hui, Kalish, Flora, Yang, Yang, Jantzie, Lauren L., Wong, Ronald J., Stevenson, David K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177474/
https://ncbi.nlm.nih.gov/pubmed/34086785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252642
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