Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers: A Nonrandomized Controlled Trial

IMPORTANCE: Most women with a BRCA1/2 pathogenic variant undergo premature menopause with potential short- and long-term morbidity due to the current method of ovarian carcinoma prevention: risk-reducing salpingo-oophorectomy (RRSO). Because the fallopian tubes play a key role in ovarian cancer path...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Steenbeek, Miranda P., Harmsen, Marline G., Hoogerbrugge, Nicoline, de Jong, Marieke Arts, Maas, Angela H. E. M., Prins, Judith B., Bulten, Johan, Teerenstra, Steven, van Bommel, Majke H. D., van Doorn, Helena C., Mourits, Marian J. E., van Beurden, Marc, Zweemer, Ronald P., Gaarenstroom, Katja N., Slangen, Brigitte F. M., Brood-van Zanten, Monique M. A., Vos, M. Caroline, Piek, Jurgen M. J., van Lonkhuijzen, Luc R. C. W., Apperloo, Mirjam J. A., Coppus, Sjors F. P. J., Massuger, Leon F. A. G., IntHout, Joanna, Hermens, Rosella P. M. G., de Hullu, Joanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176392/
https://ncbi.nlm.nih.gov/pubmed/34081085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2021.1590
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