Association of Molecular Subtypes With Differential Outcome to Apalutamide Treatment in Nonmetastatic Castration-Resistant Prostate Cancer

IMPORTANCE: There is a need to identify prognostic biomarkers to guide treatment intensification in patients with nonmetastatic castration-resistant prostate cancer (nmCRPC). OBJECTIVE: To examine whether molecular subtypes predict response to apalutamide, using archived primary tumor samples from t...

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Vydáno v:JAMA Oncol
Hlavní autoři: Feng, Felix Y., Thomas, Shibu, Saad, Fred, Gormley, Michael, Yu, Margaret K., Ricci, Deborah S., Rooney, Brendan, Brookman-May, Sabine, McCarthy, Sharon, Olmos, David, Chowdhury, Simon, Hadaschik, Boris, Liu, Yang, Davicioni, Elai, Smith, Matthew R., Small, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2021
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176389/
https://ncbi.nlm.nih.gov/pubmed/34081076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2021.1463
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