HOXA13, Negatively Regulated by miR-139-5p, Decreases the Sensitivity of Gastric Cancer to 5-Fluorouracil Possibly by Targeting ABCC4

PURPOSE: Chemoresistance remains a major challenge in the therapy of gastric cancer (GC). The homeobox (HOX) gene family has gained attention in carcinogenesis and chemoresistance. Here, this study aimed to explore the mechanism of HOXA13 in GC chemoresistance. METHODS: Quantitative real-time PCR (q...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Chen, Zhengqian, Qin, Zhiwei, Li, Lei, Wo, Qi, Chen, Xia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175971/
https://ncbi.nlm.nih.gov/pubmed/34094932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.645979
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