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The Role of Zfp467 in Mediating the Pro-osteogenic and Anti-adipogenic Effects on Bone and Bone Marrow Niche
Conditional deletion of the PTH receptor (Pth1r) in mesenchymal progenitors reduces osteoblast differentiation and bone mass while enhancing adipogenesis and bone marrow adipose tissue. Mechanistically, PTH suppresses the expression of Zfp467, a pro-adipogenic zinc finger transcription factor. Conse...
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| Publicado no: | Bone |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8175945/ https://ncbi.nlm.nih.gov/pubmed/33359894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115832 |
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