Complete Correction of Brain and Spinal Cord Pathology in Metachromatic Leukodystrophy Mice

Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder characterized by accumulation of sulfatides in both glial cells and neurons. MLD results from an inherited deficiency of arylsulfatase A (ARSA) and myelin degeneration in the central and peripheral nervous systems. Currently, no effe...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Audouard, Emilie, Oger, Valentin, Meha, Béatrix, Cartier, Nathalie, Sevin, Caroline, Piguet, Françoise
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175802/
https://ncbi.nlm.nih.gov/pubmed/34093126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.677895
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