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Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease
Chylomicron retention disease (CRD) is an autosomal recessive disorder associated with biallelic Sar1b mutations leading to defects in intracellular chylomicron (CM) trafficking and secretion. To date, a direct cause-effect relationship between CRD and Sar1b mutation has not been established, but ge...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8175419/ https://ncbi.nlm.nih.gov/pubmed/33964306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100085 |
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