Mangifera indica Extracts as Novel PKM2 Inhibitors for Treatment of Triple Negative Breast Cancer

Pyruvate kinase (PK), a key enzyme that determines glycolytic activity, has been known to support the metabolic phenotype of tumor cells, and specific pyruvate kinase isoform M2 (PKM2) has been reported to fulfill divergent biosynthetic and energetic requirements of cancerous cells. PKM2 is overexpr...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Rasul, Azhar, Riaz, Ammara, Wei, Wei, Sarfraz, Iqra, Hassan, Mudassir, Li, Jiang, Asif, Faryal, Adem, Şevki, Bukhari, Shazia Anwer, Asrar, Muhammad, Li, Xiaomeng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175167/
https://ncbi.nlm.nih.gov/pubmed/34136566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5514669
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