Mangifera indica Extracts as Novel PKM2 Inhibitors for Treatment of Triple Negative Breast Cancer

Pyruvate kinase (PK), a key enzyme that determines glycolytic activity, has been known to support the metabolic phenotype of tumor cells, and specific pyruvate kinase isoform M2 (PKM2) has been reported to fulfill divergent biosynthetic and energetic requirements of cancerous cells. PKM2 is overexpr...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Rasul, Azhar, Riaz, Ammara, Wei, Wei, Sarfraz, Iqra, Hassan, Mudassir, Li, Jiang, Asif, Faryal, Adem, Şevki, Bukhari, Shazia Anwer, Asrar, Muhammad, Li, Xiaomeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175167/
https://ncbi.nlm.nih.gov/pubmed/34136566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5514669
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