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Long non-coding RNA XIST inhibits osteoblast differentiation and promotes osteoporosis via Nrf2 hyperactivation by targeting CUL3

Osteoporosis (OP) is a common skeletal disorder characterized by a low bone mass and the deterioration of bone structure. Long non-coding (lnc)RNA X inactive-specific transcript (XIST) is highly expressed in the serum and monocytes of patients with OP. Thus, the purpose of the present study was to e...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Chen, Xiao, Ma, Fengyu, Zhai, Ning, Gao, Feng, Cao, Guijun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175064/
https://ncbi.nlm.nih.gov/pubmed/34036379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2021.4970
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