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A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis

Sepsis is a heterogeneous syndrome clinically and biologically, but biomarkers of distinct host response pathways for early prognostic information and testing targeted treatments are lacking. Olfactomedin 4 (OLFM4), a matrix glycoprotein of neutrophil-specific granules, defines a distinct neutrophil...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Kangelaris, Kirsten N., Clemens, Regina, Fang, Xiaohui, Jauregui, Alejandra, Liu, Tom, Vessel, Kathryn, Deiss, Thomas, Sinha, Pratik, Leligdowicz, Aleksandra, Liu, Kathleen D., Zhuo, Hanjing, Alder, Matthew N., Wong, Hector R., Calfee, Carolyn S., Lowell, Clifford, Matthay, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174834/
https://ncbi.nlm.nih.gov/pubmed/33355521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00090.2020
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