Gestational long-term hypoxia induces metabolomic reprogramming and phenotypic transformations in fetal sheep pulmonary arteries

Gestational long-term hypoxia increases the risk of myriad diseases in infants including persistent pulmonary hypertension. Similar to humans, fetal lamb lung development is susceptible to long-term intrauterine hypoxia, with structural and functional changes associated with the development of pulmo...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Leslie, Eric, Lopez, Vanessa, Anti, Nana A. O., Alvarez, Rafael, Kafeero, Isaac, Welsh, Donald G., Romero, Monica, Kaushal, Shawn, Johnson, Catherine M., Bosviel, Remy, Blaženović, Ivana, Song, Rui, Brito, Alex, La Frano, Michael R., Zhang, Lubo, Newman, John W., Fiehn, Oliver, Wilson, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174832/
https://ncbi.nlm.nih.gov/pubmed/33624555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00469.2020
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