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Glibenclamide does not improve outcome following severe collagenase-induced intracerebral hemorrhage in rats
Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1-Trpm4) channel implicated in edema formation. Whi...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8174736/ https://ncbi.nlm.nih.gov/pubmed/34081746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252584 |
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