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Inhibition of CMP-sialic acid transport by endogenous 5-methyl CMP

Nucleotide-sugar transporters (NSTs) transport nucleotide-sugar conjugates into the Golgi lumen where they are then used in the synthesis of glycans. We previously reported crystal structures of a mammalian NST, the CMP-sialic acid transporter (CST) (Ahuja and Whorton 2019). These structures elucida...

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Foilsithe in:PLoS One
Main Authors: Ahuja, Shivani, Cahill, James, Hartfield, Kimberly, Whorton, Matthew R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174729/
https://ncbi.nlm.nih.gov/pubmed/34081697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249905
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