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Recombinant Soluble Corin Improves Cardiac Function in Mouse Models of Heart Failure

BACKGROUND: Corin is a transmembrane protease that activates ANP and BNP (atrial and B‐type natriuretic peptides). Impaired corin expression and function are associated with heart failure. In this study, we characterized a soluble form of corin (sCorin) and examined its effects on cardiac morphology...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Niu, Yayan, Zhang, Shengnan, Gu, Xiabing, Zhou, Tiantian, Li, Feng, Liu, Meng, Wu, Qingyu, Dong, Ningzheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174325/
https://ncbi.nlm.nih.gov/pubmed/33759549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.019961
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