Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility

The decrease in contractility in myocardium adjacent (border zone; BZ) to a myocardial infarction (MI) is correlated with an increase in reactive oxygen species (ROS). We hypothesized that injection of a thermoresponsive hydrogel, with ROS scavenging properties, into the MI would decrease ROS and im...

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Published in:J Biomed Mater Res A
Main Authors: Spaulding, Kimberly A., Zhu, Yang, Takaba, Kiyoaki, Ramasubramanian, Anusuya, Badathala, Anusha, Haraldsson, Henrik, Collins, Alexander, Aguayo, Esteban, Shah, Curran, Wallace, Arthur W., Ziats, Nicholas P., Lovett, David H., Baker, Anthony J., Healy, Kevin E., Ratcliffe, Mark B.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174154/
https://ncbi.nlm.nih.gov/pubmed/32270584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36941
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