Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis

BACKGROUND: Circular RNAs (circRNAs) can act as vital players in osteoarthritis (OA). However, the roles of circRNAs in OA remain obscure. Herein, we explored the roles of exosomal circRNA bromodomain and WD repeat domain containing 1(circ-BRWD1) in OA pathology. METHODS: In vitro model of OA was co...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Arthritis Res Ther
Main Authors: Guo, Zhenye, Wang, Huan, Zhao, Feng, Liu, Min, Wang, Feida, Kang, Mingming, He, Weifu, Lv, Zhi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173917/
https://ncbi.nlm.nih.gov/pubmed/34082824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02541-8
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