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Losing DNA methylation at repetitive elements and breaking bad

BACKGROUND: DNA methylation is an epigenetic chromatin mark that allows heterochromatin formation and gene silencing. It has a fundamental role in preserving genome stability (including chromosome stability) by controlling both gene expression and chromatin structure. Therefore, the onset of an inco...

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Détails bibliographiques
Publié dans:Epigenetics Chromatin
Auteurs principaux: Pappalardo, Xena Giada, Barra, Viviana
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173753/
https://ncbi.nlm.nih.gov/pubmed/34082816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00400-z
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