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Vorapaxar in the treatment of cardiovascular diseases

Vorapaxar specifically and effectively inhibits protease activated receptor-1 and may reduce thrombin-mediated ischemic events without interfering primary hemostasis. In the TRA-2P-TIMI 50 trial, vorapaxar reduced the risk of primary ischemic outcome but with increased bleeding risk. In the post hoc...

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Detalhes bibliográficos
Publicado no:Future Cardiol
Main Authors: Tantry, Udaya S, Bliden, Kevin P, Chaudhary, Rahul, Novakovic, Marko, Rout, Amit, Gurbel, Paul A
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173497/
https://ncbi.nlm.nih.gov/pubmed/32308016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca-2019-0090
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