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Orexin/Hypocretin and Histamine Cross-Talk on Hypothalamic Neuron Counts in Mice

The loss of hypothalamic neurons that produce wake-promoting orexin (hypocretin) neuropeptides is responsible for narcolepsy type 1 (NT1). While the number of histamine neurons is increased in patients with NT1, results on orexin-deficient mouse models of NT1 are inconsistent. On the other hand, the...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Berteotti, Chiara, Lo Martire, Viviana, Alvente, Sara, Bastianini, Stefano, Bombardi, Cristiano, Matteoli, Gabriele, Ohtsu, Hiroshi, Lin, Jian-Sheng, Silvani, Alessandro, Zoccoli, Giovanna
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173058/
https://ncbi.nlm.nih.gov/pubmed/34093114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.660518
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