Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that Claudin-2 is functionally required for colorectal cancer liver metastasis and that Claudin-2 expression in primary colorectal cancers is associated with poor overall and live...

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Pubblicato in:Commun Biol
Autori principali: Tabariès, Sébastien, Annis, Matthew G., Lazaris, Anthoula, Petrillo, Stephanie K., Huxham, Jennifer, Abdellatif, Amri, Palmieri, Vincent, Chabot, Jaclyn, Johnson, Radia M., Van Laere, Steven, Verhoef, Cornelis, Hachem, Yasmina, Yumeen, Sara, Meti, Nicholas, Omeroglu, Atilla, Altinel, Gulbeyaz, Gao, Zu-Hua, Yu, Alan S. L., Grünhagen, Dirk J., Vermeulen, Peter, Metrakos, Peter, Siegel, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172859/
https://ncbi.nlm.nih.gov/pubmed/34079064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02189-9
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