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NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA

Autophagy regulates primary cilia formation, but the underlying mechanism is not fully understood. In this study, we identify NIMA-related kinase 9 (NEK9) as a GABARAPs-interacting protein and find that NEK9 and its LC3-interacting region (LIR) are required for primary cilia formation. Mutation in t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yamamoto, Yasuhiro, Chino, Haruka, Tsukamoto, Satoshi, Ode, Koji L., Ueda, Hiroki R., Mizushima, Noboru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172835/
https://ncbi.nlm.nih.gov/pubmed/34078910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23599-7
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