In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis

The alarming increase in multi- and extensively drug-resistant (MDR and XDR) strains of Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for novel, effective, and safer therapeutics. To this end, a series of 3,5-disubstituted-1,2,4-oxadiazole derivatives (3a–3i) were...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Deb, Pran Kishore, Al-Shar’i, Nizar A., Venugopala, Katharigatta N., Pillay, Melendhran, Borah, Pobitra
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172222/
https://ncbi.nlm.nih.gov/pubmed/34060396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1900162
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