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ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment

BACKGROUND: Serous ovarian cancer (SOC) is a highly lethal gynecological malignancy with poor prognosis. Given the importance of the immune-related tumor microenvironment (TME) in ovarian cancer, investigating tumor-immune interactions and identifying novel prognostic and therapeutic targets in SOC...

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Vydáno v:Front Oncol
Hlavní autoři: Ye, Xiang, An, Limei, Wang, Xiangxiang, Zhang, Chenyi, Huang, Wenqian, Sun, Chenggong, Li, Rongrong, Ma, Hanlin, Wang, Hongyan, Gao, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172172/
https://ncbi.nlm.nih.gov/pubmed/34094977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.675104
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