The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead

Immune checkpoints (ICs) have pivotal roles in regulating immune responses. The inhibitory ICs in the tumor microenvironment (TME) have been implicated in the immune evasion of tumoral cells. Therefore, identifying and targeting these inhibitory ICs might be critical for eliminating tumoral cells. V...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Hosseinkhani, Negar, Derakhshani, Afshin, Shadbad, Mahdi Abdoli, Argentiero, Antonella, Racanelli, Vito, Kazemi, Tohid, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172140/
https://ncbi.nlm.nih.gov/pubmed/34093577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.676181
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