Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11

The emergence of SARS-CoV-2 antibody escape mutations highlights the urgent need for broadly neutralizing therapeutics. We previously identified a human monoclonal antibody, 47D11, capable of cross-neutralizing SARS-CoV-2 and SARS-CoV and protecting against the associated respiratory disease in an a...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Fedry, Juliette, Hurdiss, Daniel L., Wang, Chunyan, Li, Wentao, Obal, Gonzalo, Drulyte, Ieva, Du, Wenjuan, Howes, Stuart C., van Kuppeveld, Frank J.M., Förster, Friedrich, Bosch, Berend-Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172134/
https://ncbi.nlm.nih.gov/pubmed/33958322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf5632
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