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Altered Oxidative Stress Responses and Increased Type I Collagen Expression in Bicuspid Aortic Valve Patients

BACKGROUND. The mechanisms governing extracellular matrix degradation and smooth muscle cell (SMC) loss in the ascending aorta of bicuspid aortic valve (BAV) patients are unknown. We recently reported that expression and induction of metallothionein, a reactive oxygen species scavenger, is reduced i...

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Dettagli Bibliografici
Pubblicato in:Ann Thorac Surg
Autori principali: Phillippi, Julie A., Eskay, Michael A., Kubala, Adam A., Pitt, Bruce R., Gleason, Thomas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172083/
https://ncbi.nlm.nih.gov/pubmed/21095332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2010.07.069
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