Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1

The dynamic interactions between G protein-coupled receptors (GPCRs) and their cognate protein partners are central to several cell signaling pathways. For example, the association of CXC chemokine receptor 1 (CXCR1) with its cognate chemokine, interleukin-8 (IL8 or CXCL8) initiates pathways leading...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Kharche, Shalmali, Joshi, Manali, Chattopadhyay, Amitabha, Sengupta, Durba
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172051/
https://ncbi.nlm.nih.gov/pubmed/34014914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008593
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