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Principal component analysis is limited to low-resolution analysis in cryoEM
Principal component analysis (PCA) has been widely proposed to analyze flexibility and heterogeneity in cryo-electron microscopy (cryoEM). In this paper, it is argued that (i) PCA is an excellent technique to describe continuous flexibility at low resolution (but not so much at high resolution) and...
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| Pubblicato in: | Acta Crystallogr D Struct Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
International Union of Crystallography
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171071/ https://ncbi.nlm.nih.gov/pubmed/34076596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798321002291 |
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