Therapeutic Effects of XPO1 Inhibition in Thymic Epithelial Tumors

Exportin 1 (XPO1) mediates nuclear export of many cellular factors known to play critical roles in malignant processes, and selinexor (KPT-330) is the first XPO1-selective inhibitor of nuclear export compound in advanced clinical development phase for cancer treatment. We demonstrated here that inhi...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Conforti, Fabio, Zhang, Xu, Rao, Guanhua, De Pas, Tommaso, Yonemori, Yoko, Rodriguez, Jose Antonio, McCutcheon, Justine N., Rahhal, Raneen, Alberobello, Anna T., Wang, Yisong, Zhang, Yu-Wen, Guha, Udayan, Giaccone, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170838/
https://ncbi.nlm.nih.gov/pubmed/28819023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1323
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