ONCOGENE PANEL SEQUENCING ANALYSIS IDENTIFIES CANDIDATE ACTIONABLE GENES IN ADVANCED WELL-DIFFERENTIATED GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS

OBJECTIVE: To report the rate of candidate actionable somatic mutations in patients with locally advanced and metastatic gastro-enteropancreatic (GEP) neuroendocrine tumors (NET) and of other genetic alterations that may be associated with tumorigenesis. METHODS: A phase II mutation targeted therapy...

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Pubblicato in:Endocr Pract
Autori principali: Tirosh, Amit, Killian, J. Keith, Zhu, Yuelin Jack, Petersen, David, Walling, Jennifer, Mor-Cohen, Ronit, Neychev, Vladimir, Stevenson, Holly, Keutgen, Xavier M., Patel, Dhaval, Nilubol, Naris, Meltzer, Paul, Kebebew, Electron
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170837/
https://ncbi.nlm.nih.gov/pubmed/30865533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4158/EP-2018-0603
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