Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

BACKGROUND: Preferentially expressed antigen in melanoma (PRAME) is a cancer/testis antigen (CTA) that is predominantly expressed in normal gametogenic tissues and a variety of tumors. Members of the PRAME gene family encode leucine-rich repeat (LRR) proteins that provide a versatile structural fram...

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Bibliografiske detaljer
Udgivet i:Cell Biosci
Main Authors: Liu, Wan-Sheng, Lu, Chen, Mistry, Bhavesh V.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170798/
https://ncbi.nlm.nih.gov/pubmed/34074333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00612-6
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