AML-derived Extracellular Vesicles Confer De Novo Chemoresistance to Leukemic Myeloblast Cells by Promoting Drug Export Genes Expression and ROS Inhibition

In spite of successful initial remission, chemo-resistance and relapse are still concerning points in acute myeloid leukemia (AML) treatment strategies. Multidrug resistance (MDR) appears to be the major contributor of chemo-resistance, arising in some sub-clones of cancers and could be developed in...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Barzegar, Mohieddin, Allahbakhshian Farsan, Mehdi, Amiri, Vahid, Mohammadi, Saeed, Shahsavan, Shaghayegh, Mirzaeian, Amin, Mohammadi, Mohammad Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170774/
https://ncbi.nlm.nih.gov/pubmed/34400967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2020.113272.14199
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