Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial

IMPORTANCE: The current standard induction therapy for antineutrophil cytoplasm antibody (ANCA)–associated vasculitis is the combination of high-dose glucocorticoids and cyclophosphamide or rituximab. Although these regimens have high remission rates, they are associated with considerable adverse ev...

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Detalles Bibliográficos
Publicado en:JAMA
Main Authors: Furuta, Shunsuke, Nakagomi, Daiki, Kobayashi, Yoshihisa, Hiraguri, Masaki, Sugiyama, Takao, Amano, Koichi, Umibe, Takeshi, Kono, Hajime, Kurasawa, Kazuhiro, Kita, Yasuhiko, Matsumura, Ryutaro, Kaneko, Yuko, Ninagawa, Keita, Hiromura, Keiju, Kagami, Shin-ichiro, Inaba, Yosuke, Hanaoka, Hideki, Ikeda, Kei, Nakajima, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: American Medical Association 2021
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170547/
https://ncbi.nlm.nih.gov/pubmed/34061144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2021.6615
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