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Case Report: A Rare Case of Autoinflammatory Phospholipase Cγ2 (PLCγ2)-Associated Antibody Deficiency and Immune Dysregulation Complicated With Gangrenous Pyoderma and Literature Review

BACKGROUND: Autoinflammatory phospholipase Cγ2 (PLCγ2)-associated antibody deficiency and immune dysregulation (APLAID) is a rare autoinflammatory disease caused by gain-of-function mutations in the PLCG2 gene. Here we report a rare case of APLAID patient carrying a novel heterozygous missense PLCG2...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Na, Zhang, Bingqing, Wang, Tao, Shen, Min, Zeng, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170136/
https://ncbi.nlm.nih.gov/pubmed/34093563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.667430
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