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Incidence and Risk Factors of Hepatic Fibrosis in Psoriatic Patients Receiving Methotrexate with Concomitant Acitretin Therapy and Methotrexate Monotherapy

BACKGROUND: The use of methotrexate-acitretin (MTX-ACI) combination therapy in treating psoriasis has been limited due to concerns related to hepatic fibrosis. However, in vitro evidence revealed a protective effect of acitretin in methotrexate (MTX)-induced liver fibrosis. OBJECTIVE: This study aim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Rattanakaemakorn, Ploysyne, Pinyowiwat, Prinpat, Iamsumang, Wimolsiri, Chanprapaph, Kumutnart, Suchonwanit, Poonkiat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170124/
https://ncbi.nlm.nih.gov/pubmed/34093007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S304168
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