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Senescent T cells: a potential biomarker and target for cancer therapy

The failure of T cells to eradicate tumour cells in the tumour microenvironment is mainly due to the dysfunction of T cells. Senescent T cells, with defects in proliferation and effector functions, accumulate in ageing, chronic viral infections, and autoimmune disorders where antigen stimulation per...

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Publicat a:EBioMedicine
Autors principals: Zhang, Jie, He, Tianhui, Xue, Lixiang, Guo, Hongyan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170103/
https://ncbi.nlm.nih.gov/pubmed/34049248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103409
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