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EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

Interleukin 9 (IL-9)-producing helper T (Th9) cells are essential for inducing anti-tumor immunity and inflammation in allergic and autoimmune diseases. Although transcription factors that are essential for Th9 cell differentiation have been identified, other signaling pathways that are required for...

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Publicat a:Nat Commun
Autors principals: Roy, Suyasha, Rizvi, Zaigham Abbas, Clarke, Alexander J., Macdonald, Felicity, Pandey, Abhaydeep, Zaiss, Dietmar Martin Werner, Simon, Anna Kathrina, Awasthi, Amit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169867/
https://ncbi.nlm.nih.gov/pubmed/34075041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23042-x
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