Drug screening with zebrafish visual behavior identifies carvedilol as a potential treatment for an autosomal dominant form of retinitis pigmentosa

Retinitis Pigmentosa (RP) is a mostly incurable inherited retinal degeneration affecting approximately 1 in 4000 individuals globally. The goal of this work was to identify drugs that can help patients suffering from the disease. To accomplish this, we screened drugs on a zebrafish autosomal dominan...

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Udgivet i:Sci Rep
Main Authors: Ganzen, Logan, Ko, Mee Jung, Zhang, Mengrui, Xie, Rui, Chen, Yongkai, Zhang, Liyun, James, Rebecca, Mumm, Jeff, van Rijn, Richard M., Zhong, Wenxuan, Pang, Chi Pui, Zhang, Mingzhi, Tsujikawa, Motokazu, Leung, Yuk Fai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169685/
https://ncbi.nlm.nih.gov/pubmed/34075074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89482-z
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