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A comparison of focused and unfocused ultrasound for microbubble-mediated gene delivery

We compared focused and unfocused Ultrasound Targeted Microbubble Destruction (UTMD) for delivery of reporter plasmids to the liver and heart in mice. Optimal hepatic expression was seen with double-depth targeting at 5 and 13mm in vivo, and incorporated a low pulse repetition frequency and short pu...

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Detalhes bibliográficos
Publicado no:Ultrasound Med Biol
Main Authors: Anderson, Cynthia D., Walton, Chad B., Shohet, Ralph V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169610/
https://ncbi.nlm.nih.gov/pubmed/33812691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2021.02.016
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