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Deciphering transcriptional and functional heterogeneity in hematopoiesis with single-cell genomics

PURPOSE OF REVIEW: Single-cell genomic approaches have uncovered cell fate biases and heterogeneity within hematopoietic subpopulations. However, standard single-cell transcriptomics suffers from high sampling noise, which particularly skews the distribution of lowly expressed genes, such as transcr...

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Bibliografske podrobnosti
izdano v:Curr Opin Hematol
Main Authors: Martin-Rufino, Jorge D., Sankaran, Vijay G.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169609/
https://ncbi.nlm.nih.gov/pubmed/33901135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000657
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