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Deciphering transcriptional and functional heterogeneity in hematopoiesis with single-cell genomics

PURPOSE OF REVIEW: Single-cell genomic approaches have uncovered cell fate biases and heterogeneity within hematopoietic subpopulations. However, standard single-cell transcriptomics suffers from high sampling noise, which particularly skews the distribution of lowly expressed genes, such as transcr...

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Detalhes bibliográficos
Publicado no:Curr Opin Hematol
Main Authors: Martin-Rufino, Jorge D., Sankaran, Vijay G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169609/
https://ncbi.nlm.nih.gov/pubmed/33901135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000657
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