X chromosome contribution to the genetic architecture of primary biliary cholangitis

BACKGROUND & AIMS: Genome-wide association studies (GWAS) in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually-dimorphic complex autoimmune disease. METHODS: We pe...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Asselta, Rosanna, Paraboschi, Elvezia Maria, Gerussi, Alessio, Cordell, Heather J., Mells, George F., Sandford, Richard N., Jones, David E., Nakamura, Minoru, Ueno, Kazuko, Hitomi, Yuki, Kawashima, Minae, Nishida, Nao, Tokunaga, Katsushi, Nagasaki, Masao, Tanaka, Atsushi, Tang, Ruqi, Li, Zhiqiang, Shi, Yongyong, Liu, Xiangdong, Xiong, Ma, Hirschfield, Gideon, Siminovitch, Katherine A., Carbone, Marco, Cardamone, Giulia, Duga, Stefano, Gershwin, M. Eric, Seldin, Michael F., Invernizzi, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169555/
https://ncbi.nlm.nih.gov/pubmed/33675743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.02.061
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