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The discovery and development of IP3 receptor modulators: An update.
INTRODUCTION: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular calcium (Ca(2+)) release channels located on the endoplasmic/sarcoplasmic reticulum. The availability of the structure of the ligand-binding domain of IP3Rs has enabled the design of compatible ligands, but the limiting s...
Uloženo v:
| Vydáno v: | Expert Opin Drug Discov |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8169518/ https://ncbi.nlm.nih.gov/pubmed/33356639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2021.1858792 |
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