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The discovery and development of IP3 receptor modulators: An update.
INTRODUCTION: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular calcium (Ca(2+)) release channels located on the endoplasmic/sarcoplasmic reticulum. The availability of the structure of the ligand-binding domain of IP3Rs has enabled the design of compatible ligands, but the limiting s...
Tallennettuna:
| Julkaisussa: | Expert Opin Drug Discov |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8169518/ https://ncbi.nlm.nih.gov/pubmed/33356639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2021.1858792 |
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