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Limitations of the fasting proinsulin to insulin ratio as a measure of β-cell health in people with and without impaired glucose tolerance.

The fasting proinsulin to insulin ratio is elevated in people with type 2 diabetes and has been suggested as a marker of β–cell health. However, its utility in discriminating between individuals with varying degrees of β–cell dysfunction is unclear. Proinsulin has a very different half-life to insul...

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Détails bibliographiques
Publié dans:Eur J Clin Invest
Auteurs principaux: Egan, Aoife M., Laurenti, Marcello C., Andrade, M. Daniela Hurtado, Man, Chiara Dalla, Cobelli, Claudio, Bailey, Kent R., Vella, Adrian
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169515/
https://ncbi.nlm.nih.gov/pubmed/33289929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eci.13469
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