Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients

Thrombocytopenic disorders have been treated with the Thrombopoietin-receptor agonist Eltrombopag. Patients with the same apparent form of thrombocytopenia may respond differently to the treatment. We describe a miniaturized bone marrow tissue model that provides a screening bioreactor for personali...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Di Buduo, Christian A, Laurent, Pierre-Alexandre, Zaninetti, Carlo, Lordier, Larissa, Soprano, Paolo M, Ntai, Aikaterini, Barozzi, Serena, La Spada, Alberto, Biunno, Ida, Raslova, Hana, Bussel, James B, Kaplan, David L, Balduini, Carlo L, Pecci, Alessandro, Balduini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169123/
https://ncbi.nlm.nih.gov/pubmed/34059198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58775
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