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TGF-β inhibition can overcome cancer primary resistance to PD-1 blockade: A mathematical model

Immune checkpoint inhibitors have demonstrated, over the recent years, impressive clinical response in cancer patients, but some patients do not respond at all to checkpoint blockade, exhibiting primary resistance. Primary resistance to PD-1 blockade is reported to occur under conditions of immunosu...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Siewe, Nourridine, Friedman, Avner
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168900/
https://ncbi.nlm.nih.gov/pubmed/34061898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252620
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