Structure elucidation and docking analysis of 5M mutant of T1 lipase Geobacillus zalihae

5M mutant lipase was derived through cumulative mutagenesis of amino acid residues (D43E/T118N/E226D/E250L/N304E) of T1 lipase from Geobacillus zalihae. A previous study revealed that cumulative mutations in 5M mutant lipase resulted in decreased thermostability compared to wild-type T1 lipase. Mult...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ishak, Siti Nor Hasmah, Kamarudin, Nor Hafizah Ahmad, Ali, Mohd Shukuri Mohamad, Leow, Adam Thean Chor, Shariff, Fairolniza Mohd, Rahman, Raja Noor Zaliha Raja Abd
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168862/
https://ncbi.nlm.nih.gov/pubmed/34061877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251751
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