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(15)N CPMG relaxation dispersion for the investigation of protein conformational dynamics on the μs‐ms timescale

Protein conformational dynamics play fundamental roles in regulation of enzymatic catalysis, ligand binding, allostery, and signaling, which are important biological processes. Understanding how the balance between structure and dynamics governs biological function is a new frontier in modern struct...

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Vydáno v:J Vis Exp
Hlavní autoři: Singh, Aayushi, Purslow, Jeffrey A., Venditti, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168574/
https://ncbi.nlm.nih.gov/pubmed/33938889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/62395
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