A frequent nonsense mutation in exon 1 across certain HLA-A and HLA-B alleles in leukocytes of patients with acquired aplastic anemia

Leukocytes that lack expression of HLA alleles are frequently detected in patients with acquired aplastic anemia (AA) who respond to immunosuppressive therapy, although the exact mechanisms underlying the HLA loss and HLA allele repertoire likely to acquire loss-of-function mutations are unknown. We...

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Bibliografski detalji
Izdano u:Haematologica
Glavni autori: Mizumaki, Hiroki, Hosomichi, Kazuyoshi, Hosokawa, Kohei, Yoroidaka, Takeshi, Imi, Tatsuya, Zaimoku, Yoshitaka, Katagiri, Takamasa, Nguyen, Mai Anh Thi, Tran, Dung Cao, Elbadry, Mahmoud Ibrahim Yousef, Chonabayashi, Kazuhisa, Yoshida, Yoshinori, Takamatsu, Hiroyuki, Ozawa, Tatsuhiko, Azuma, Fumihiro, Kishi, Hiroyuki, Fujii, Yoichi, Ogawa, Seishi, Tajima, Atsushi, Nakao, Shinji
Format: Artigo
Jezik:Inglês
Izdano: Fondazione Ferrata Storti 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168509/
https://ncbi.nlm.nih.gov/pubmed/32439725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2020.247809
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