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Activated mesangial cells induce glomerular endothelial cells proliferation in rat anti‐Thy‐1 nephritis through VEGFA/VEGFR2 and Angpt2/Tie2 pathway

OBJECTIVES: We aimed to investigate the underlying mechanism of endothelial cells (ECs) proliferation in anti‐Thy‐1 nephritis. MATERIALS AND METHODS: We established anti‐Thy‐1 nephritis and co‐culture system to explore the underlying mechanism of ECs proliferation in vivo and in vitro. EdU assay kit...

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Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Zhao, Yinghua, Fu, Bo, Chen, Pu, Li, Qinggang, Ouyang, Qing, Zhang, Chuyue, Cai, Guangyan, Wu, Lingling, Chen, Xiangmei
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168418/
https://ncbi.nlm.nih.gov/pubmed/33987885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13055
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