Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway

OBJECTIVES: The effects of general anaesthetics on fetal brain development remain elusive. Radial glial progenitors (RGPs) generate the majority of neurons in developing brains. Here, we evaluated the acute alterations in RGPs after maternal sevoflurane exposure. METHODS: Pregnant mice were exposed...

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Veröffentlicht in:Cell Prolif
Hauptverfasser: Jiang, Ming, Tang, Tianxiang, Liang, Xinyue, Li, Juchen, Qiu, Yue, Liu, Shiwen, Bian, Shan, Xie, Yunli, Fang, Fang, Cang, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168415/
https://ncbi.nlm.nih.gov/pubmed/33955094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13042
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